It is 200 years since Ellen Ripley sacrificed herself to destroy the alien queen on Fiorina 161. Ripley's former employers, the Weyland-Yutani Company has dissolved and now the United Systems Military has assumed the task of breeding and harnessing the deadly aliens. With blood samples taken from her previous life, scientists clone a new Ripley in order to extract the alien queen inside of her. The new Ripley, known as Number 8, acquires physical and emotional traits from both humanity and the aliens, making her question where her allegiances lie. Shortly after, the aliens break free and commence killing those onboard. Along with a crew of smugglers that unknowingly helped in delivering hosts to breed the alien species, Ripley must now escape the perilous ship. Along the way, Ripley encounters a shocking revelation that truly sets herself against both humanity and the alien species. She must now decide what she truly is, in order to save humanity once more.