After countless lonely nights over a bottle of wine and "The Bachelor", Seattle longtime friends Kate, a high school English teacher, and Meg, an ambitious cosmetics saleswoman, realize that they are going through a rough patch. To take a break, the pair take an impromptu flight to Fort Lauderdale and find themselves seated next to handsome blond Ryan, who is on his way to a friend's wedding. Suddenly the best friends get sucked into a destructive spiral of relentless competition and cut-throat one-upmanship with Ryan as the prize, especially when a Category 4 hurricane reroutes their flight to a St. Louis layover. They say all is fair in love and war, but is Ryan worth Meg and Kate's years of friendship?