Imagine having to win over the girl of your dreams...every single day. That's the dilemma that playboy Honolulu veterinarian Henry Roth faces when after a multitude of one-night stands, he decides to settle down after a chance meeting with local artist Lucy Whitmore. Unfortunately for him, Lucy has short-term memory loss stemming from a car accident that happened a year earlier on her father Marlin's birthday; consequently, she can't remember anything that happened the day before, so each day, Henry must attempt to win her heart again. Additionally, Lucy's friends and family, including her older brother Doug, are very protective, so Henry must do everything possible to convince them that he's doing it for all the right reasons.