Milan, 1978. Over the protests of his ailing, haughty father, Maurizio D'Ancora, handsome heir and law student Maurizio Gucci embarks on a whirlwind romance with Patrizia Reggiani, an assertive middle-class arriviste. As the young couple builds a future together, Patrizia immediately gains an unexpected ally in the shape of sly Uncle Aldo and, little by little, gets her hooks into the Gucci fashion empire. Now, whoever is not with Patrizia is against her. But couples should stay together for richer or for poorer, in sickness and in health. However, can the glamorous House of Gucci survive Patrizia's subtle machinations?