When two immortals meet in the long-ago past, the destiny of mankind is changed forever. For a thousand years, Doro has cultivated a small African village, carefully breeding its people in search of seemingly unattainable perfection. He survives through the centuries by stealing the bodies of others, a technique he has so thoroughly mastered that nothing on Earth can kill him. Doro is an entity who changes bodies like clothes, killing his hosts by reflexor design. He fears no one…until he meets Anyanwu. Anyanwu is a shapeshifter who can absorb bullets & heal with a kiss & savage anyone who threatens her. A centuries-old woman whose means of immortality are as kind as his are cruel. She is capable of healing with a kiss, and she recognizes Doro as a tyrant. Though many humans have tried to kill them, these two demi-gods have never before met a rival. Now they begin a struggle that will last centuries & permanently alter the nature of humanity.